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They work via an epigenetic mechanism, entering the cell nucleus to modulate gene expression and restore the normal protein synthesis of a specific organ, thereby normalizing its function

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Rodents with induced hippocampal lesions, scopolamine-induced amnesia, or age-related cognitive decline show robust dose-dependent improvements

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In particular, it was hypothesized that an altered metabolism of folate, resulting from the presence of polymorphisms in metabolic genes, could lead to aberrant methylation of peri-centromeric regions of chromosome 21, favoring its abnormal segregation during maternal meiosis and leading to the formation of eggs with two copies of chromosome 21, which, if fertilized, would result in a zygote with full trisomy for chromosome 21 (James et al., 1999

Myelin is the fatty insulating layer that wraps around nerve axons, enabling rapid and efficient electrical signal transmission