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If cleaning doesn't completely get the smell out, they'll have to be replaced

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For macrophage polarization, NOX2-dependent ROS generation may be involved in the polarization pathway of primary macrophages to the M2 phenotype, linked to the high-mobility group box 1 (HMGB1)/Toll-like receptor 2 (TLR2)/NOX2 autophagy axis (93)

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