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The remainder consists of Honduran tobaccos, including leaves from the Trojes, Azacualapa, and Jamastran Valley regions

Tobacco smoke is one of the leading causes of and high-risk factors for lung cancer

McCormack C, Hutchinson D, Burns L, Youssef G, Wilson J, Elliott E, Allsop S, Najman J, Jacobs S, Rossen L, Olsson C & Mattick R

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Biomarkers of health effects PMI researchers reported a controlled clinical study that applied systems pharmacology and showed that exposure-response gene signature in blood was similarly reduced in smoking cessation or switching to IQOS groups compared to continued smoking 98