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The limbic-dopaminergic system, tasked with regulating emotional and reward-driven behaviors, undergoes expansion in adolescence and is particularly vulnerable to nicotine induced damage during this developmental period [91]

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For instance, researchers identified that us, the average user of vapour products prefer terms such as vape or ecig to refer to our hardware instead of Electronic Nicotine Delivery System (ENDS)

In addition to tumorigenesis, smoking may also lead to poor surgical outcomes, prolonged recovery periods, increased complication rate, poor response to chemotherapy, and potentially have an impact on recurrence [5,6,7,8]