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This significant expansion is primarily fueled by global regulatory shifts, such as the EU TPD and FDA menthol bans, which are strategically redirecting consumer demand towards innovative flavor accessories

It has been reported that cigarette smoke along with LPS leads to over-expression of proinflammatory cytokines such as interleukin (IL) 1, tumor necrosis factor- (TNF-), IL-6 and interferon- (INF-)

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Villanti et al., How Do We Determine the Impact of Ecigarettes on Cigarette Smoking Cessation or Reduction