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On one hand, autophagy can maintain cellular metabolic balance and survival by clearing damaged organelles and proteins, thereby promoting tumor cell survival and drug resistance in certain contexts ( The interaction between autophagy and apoptosis is particularly complex in tumor cells and HGSOC cells

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Day EK, Sosale NG, Lazzara MJ (2016) Cell signaling regulation by protein phosphorylation: a multivariate, heterogeneous, and context-dependent process