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Such changes in appetite-regulating hormones might have contributed to the sustained weight loss and changes in the control of eating questionnaire responses observed in STEP 5 over a 2-year period 49,50

doi: 10.1038/nrn.2018.8 58 HanWTellezLAPerkinsMHPerezIOQuTFerreiraJet al

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When used under medical supervision, semaglutide GLP-1 can help reduce hunger, increase feelings of fullness, and support significant weight loss by decreasing calorie intake