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Findings from the Framingham Heart Study, a large community-based cohort including offspring and third-generation participants, revealed that choline intake, calculated as the sum of dietary choline-containing compounds including phosphocholine, sphingomyelin, free choline, glycerophosphocholine, and PC, was inversely associated with NAFLD risk (159)

For now, to the best of our knowledge, despite the extensive literature supporting its usefulness, TMAO has not been identified as an established biomarker in CAD or HF guidelines

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Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: disturbing cholesterol homeostasis and post-translational modification of proteins