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When the ratio of good to bad microbes is off, your gut is in dysbiosis. Dysbiosis leads to leaky gut, which means the tight junctions along your gut lining loosen, the cells along this protective wall spread apart, and larger inflammatory molecules (like bacteria) can therefore leak into your bloodstream

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Neuroprotective and neurorestorative effects of Thymosin -4 after central nervous system injury.Annals of the New York Academy of Sciences , 1194, 185-192