I would also assume a 100ml bottle would last you nearly a lifetime
specified by CMS
A population-based case-control investigation on cancers of the oral cavity in Bangalore, India
doi:10.5005/jp-journals-10024-2058
Oral Contraceptives High estrogen levels from oral contraceptives may disrupt normal healing processes and increase the risk of dry socket

The authors describe that after adjusting for age, sex, comorbidities, serum albumin, shared frailty by study sites, and PD vintage, poor oral health was associated with increased risks of peritonitis (adjusted hazard ratio [HR] = 1.45, 95 percent confidence interval [CI]: 1.06-2.00) and all-cause mortality (adjusted HR = 1.55, 95 percent CI: 1.04-2.32) but not hemodialysis (HD) transfer (adjusted HR = 1.89, 95 percent CI: 0.87-4.10) compared to participants with good oral health. Furthermore, the study explained that poor oral health status was present in one-fourth of peritoneal dialysis patients and was independently associated with a higher risk of peritonitis and death. [205] Moreover, submitters provided information that suggests that patients with ESRD receiving hemodialysis services and receiving preventive oral and dental services experience increased survival while those not receiving dental services were associated with increased mortality