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We demonstrated that, at low doses (ng), local (intraplantar) or systemic (intraperitoneal) injections of thymulin resulted in hyperalgesia with an increase in proinflammatory mediators, and that this peptide could act directly on the afferent nerve terminals through prostaglandinE2 (PGE2)dependent mechanisms, thus forming a neuroimmune loop involving capsaicinsensitive primary afferent fibers

Regulates brain serotonin and dopamine functions, possibly helping with mood

296 , G1140G1149 (2009)

The nutritional supplement should not be used as a substitute for a varied diet

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Very high doses of L-carnitine can cause undesirable side effects such as diarrhea or headaches