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Bonnie Springs at Hines Hospital, VA Medical Center, gave depressed and non-depressed subjects either nicotinized or denicotinized cigarettes after introducing a positive mood trigger and found that [s]elf-administering nicotine appears to improve depression-prone smokers emotional response to a pleasant stimulus. To investigate further, researchers at the University of Pittsburgh studied whether or not cigarettes improve emotional response to stressful triggers such as preparing for public speaking, dealing with a difficult computer task, and seeing negative images

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The findings build on previous research that established relationships between smoking and Alzheimers Disease and other forms of dementia, and could point to an opportunity to identify signs of trouble earlier in life, said Jenna Rajczyk, lead author of the study, which appears in the Journal of Alzheimers Disease