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G., & Ueda, H

Phase 2 trial data reported modest increases in heart rate in some participants

Some patients choose occasional treatments, while others follow a structured wellness plan

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In older patients with primary carnitine deficiency there is a strong likelihood for skeletal myopathy, cardiomyopathy sometimes associated with hypotonia, and arrhythmias leading to sudden death

In addition, it was reported that the cells with higher expression levels of auxin response factor (ARF) were more susceptive to ferroptosis, as ARF could inhibit the ability of NRF2 to activate its target genes, including SLC7A11 (Liu et al., 2020)