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Most pharmacogenomic risk factors for DILI reside in the HLA region on chromosome 6 and are often drug-specific

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Kraft VAN, Bezjian CT, Pfeiffer S, Ringelstetter L, Mller C, Zandkarimi F, Merl-Pham J, Bao X, Anastasov N, Kssl J, et al

In addition, it has long been known that GSH is capable of forming disulfide bonds with cysteine residues of proteins, and the relevance of this mechanism (S-glutathionylation) in regulation of protein function has been well documented in a number of research fields

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