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The situation in Switzerland According to the Federal Council, the harmful effects of littered cigarette butts to the environment have not been adequately documented

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The methodology of generating the cigarette smoke extracts (CSEs) from combustible cigarettes and HTPs was described in prior research and, as the authors note, allows investigators to use the same solution for in vitro and in vivo studies, ensuring that the cells and animals are exposed to the same molecules, and making it possible to dilute the CSE to different concentrations

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