While studies attempting to localize the pathology in FMS to peripheral tissues have failed in showing any abnormalities in muscle tissue, Staud and coworkers did show that enhanced central pain processing can occur via continued peripheral muscle afferent input, Their study demonstrated that muscle lidocaine injections increased local pain thresholds and decreased remote secondary heat hyperalgesia in fibromyalgia patients, emphasizing the important role of peripheral impulse input in maintaining central sensitization
Even tho i have decreased pain in both treated areas another issues popped out that require attention
Wrong peptide sequences may have entirely unpredictable effects
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There is one small pilot study in humans (examining knee pain, where 7 of 12 participants reported sustained improvement beyond 6 months) and a 2025 safety study confirming BPC-157 was well tolerated in healthy adults
Heart Health: Vitamin B12 helps lower levels of homocysteine, an amino acid in the blood that, at high levels, can be a risk factor for heart disease