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Dimensions: 5242 x 3488 px | 44.4 x 29.5 cm | 17.5 x 11.6 inches | 300dpi Date taken: 12 April 2005

135 Very recently, Nakamura et al

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Second, smoking-associated or methylation-associated confounding factors, such as alcohol consumption and body mass index, which were not adjusted for in many of the studies we included, may contribute to the heterogeneity