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CDC and FDA encourage the public to submit detailed reports of any unexpected health or product issues related to tobacco or e-cigarette products to the FDA via the online Safety Reporting Portal
Potential confounders were selected using directed acyclic graphs (DAGs) [27] based on our a priori knowledge of the relationships among potential confounders, intermediate variables, exposure, and outcome variables, as well as on existing information regarding factors associated with CVD and tobacco consumption [28, 29]
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L., & McKee, S