Use a new needle for each injection to prevent contamination, infection, and ensure the medication is delivered correctly
Tirzepatide-specific notes: Because it's a dual agonist with stronger effects on appetite, some people experience slightly more gastrointestinal side effects initially, particularly nausea
In that role it is meant to reduce peptide breakdown during manufacturing, storage, and the weeks before use
So while it can happen, its still considered uncommon
Are compounded versions safe
A 2025 narrative review of clinical trials confirmed that across completed randomised and indirect comparisons, tirzepatide consistently outperforms semaglutide in body weight and HbA1c reduction [2]