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a process in which the body needs more and more of a drug to get the same effect

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However, despite the devastating effects of tobacco use, only a handful of countries currently regulate tobacco products, including on how the product is made, the contents of the product and emissions from tobacco products during us, to which users and bystanders can be exposed

When we also added a smoking-by-period interaction, the main effects of both smoking and period were statistically significant, but the interaction was not

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