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February 2024, KT&G, South Korea's leading cigarette maker, announced that its ultra-slim Esse brand exceeded 900 billion cumulative sales in 2023, with 405.1 billion sold abroad

The study also showed that even short-term exposure to these chemicals can alter cellular pathways linked to energy production, DNA repair, and structural integrity

It is known that this chemical induces tolerance and overtime show reduced effectiveness, making dyskinesias reappear 56,57

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