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Official FDA research as to the long-term health effects of using e-cigarettes is lacking, but that's likely to change as more people take up vaping

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Last year, the Commission published a report summarizing and measuring the effectiveness of More About Marijuana, and currently, the agencys Research and Communications teams are working with MORE Advertising to inform future direct-to-youth campaign content about the risks of underage consumption

But per a 2005 study on whether coffee and cigarettes can have a laxative effect, the researchers found that while both coffee and warm water have an effect on defecation by increasing rectal tone, nicotine didnt affect rectal tone any more than a placebo

A previous pilot study indicated that the split-half reliability coefficient of the questionnaire was 0.87, and the content validity coefficient was 0.85, which was reported in our previous work 18

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