E-cigarettes and asthma Chronic inflammation and airway hyperresponsiveness are key pathophysiological features of bronchial asthma, characterized by increased reactivity of the airways to non-specific stimuli, leading to airway smooth muscle contraction, increased airway resistance, and airflow limitation [65]
Since the plasma half-life of nicotine is 2 hours 18 , we did not record the number and duration of cigarettes smoked
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