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Tobacco Control 22(2):6673

The evidence suggests an association and plausible biological mechanisms, but more research is needed to fully characterise this relationship

Most Nicotiana species are grown as annuals in climates where winters are cold as Nicotiana are sensitive to frost

Additionally, and as discussed in section V, the current Surgeon General's warnings often go unnoticed and are not effective at informing the public of the health risks associated with cigarette smoking B

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According to DPH estimates, more than 7,000 youths a year in Massachusetts become addicted to cigarettes, and smoking kills 8,000 residents annually