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The primary endpoint is the time to the first occurrence of a composite primary outcome event, defined as a persistent eGFR decline (50% from baseline), reaching ESRD, renal death, or CV death

This approach may help identify the most cost-effective and clinically appropriate GLP-1 pathway forward, whether through insurance formulary negotiation, compounded medication, or hybrid strategies

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Key players in this phase include major pharma sponsors, Contract Research Organizations (CROs), clinical trial networks, and regulatory consultants

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Expanding treatment options gives clinicians greater flexibility to tailor care to individual patient needs and preferences