Rather, our electrophysiology data define ionocytes as critical for homeostatic ion transport in the human airway epithelium in a fashion that involves other channels/transporters, but may still include CFTR
Unlike conventional in vitro systems, the CFAX12 better mimics the in-vivo smoke inhalation situation, with the alveolar epithelial cells cultured at ALI, being directly exposed to the smoke rather than cigarette smoke extract (CSE) in liquid form
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