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Simulating this hormone, compounded GLP-1 can contribute to weight loss by reducing cravings, increasing feelings of fullness, and delaying food digestion and gastric emptying

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doi: 10.1381/096089206778026415

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Ovary-on-a-chip models, ex vivo follicular cultures, and human in vitro studies employing granulosa cells from both PCOS and non-PCOS patients could clarify whether the clinically observed ovarian benefits are dependent on metabolic disruption or if GLP-1RAs affect ovarian physiology independently of systemic metabolic conditions