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This may help reduce the likelihood of gastrointestinal discomfort

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Efficacy results include binding affinity and stability in forming complexes with viral enzymes, potential multi-target inhibitory activity against SARS-CoV-2, non-competitive modulation and destabilization of interactions between viral spike protein and hACE2 receptor, interactions with key viral protein residues suggesting inhibitory potential, disruption of virushost interaction and inhibition of viral replication, modulation of host immune response against SARS-CoV-2, inhibition of viral entry through interaction with key viral protein residues, potential as a multi-target inhibitor against SARS-CoV-2 and inhibition of SARS-CoV-2-hACE2 interaction, suggesting a possible role for hesperidin in preventing viral entry into cells

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