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Ca2+ provides favorable features as a secondary messenger and serves as one of the major components in the cellular signaling pathways of many organisms (Sanders et al., 1999)

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Although typically considered second-line therapy, SGLT2 inhibitors may have a role as initial pharmacological treatment in type 2 diabetes in conjunction with metformin in appropriately selected patients (Donnan 2019

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Microsomes (1 mg/ml) in sodium phosphate buffer, pH 7.4 were supplemented with NADPH (10 mM) and NFT (5 mM)

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