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In contrast, hypoglycemia is uncommon with insulin sensitizers and GLP-1 analogs, allowing the physician to titrate these drugs to maximum dosage to reduce HbA1c levels below 6.0%

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doi: 10.1016/j.bbaexp.2005.02.003 161 YangW

All post-dose glucose levels remained within the normal reference range for the laboratory, and no adverse events of hypoglycemia were reported

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Taken together, these findings suggest that GLP-1s may support longevity not just by reducing weight, but by improving the quality and metabolic stability of the years ahead