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This leads to reduced calorie intake and gradual weight loss

2015, pp

A role of the inflammasome in the low storage capacity of the abdominal subcutaneous adipose tissue in obese adolescents

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(HEALTHLINE: Losing weight on GLP-1 drugs like Ozempic, Wegovy, Mounjaro, and Zepbound may increase your risk of developing nutrient deficiencies) Tirzepatide has a dual approach with both GLP and GIP benefits

It is important to note that all current evidence derives from in vitro cellular models and in vivo animal studies, and no human clinical trials have been conducted as of February 2026