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The researchers identify that these products are clearly aimed at cigarette smokers

Tobacco products whether it is in the form of shisha, cigarette or others contain nicotine, while nicotine is a highly addictive substance

Psychoneuroendocrinology 35 , 11331141 (2010)

Its called epigenetics and in general, those (modifications) are associated with more chronic conditions. Snyder uses himself as an example

Although smokers are warned on the dangers of smoking on the cigarette packs, they have repeatedly ignored this notion, and though avoidable, cigarette smoking has continued to cause deaths and disability across the world