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Combined activation of GLP-1, GIP, and GCG systems theoretically provides complementary mechanisms: GLP-1-mediated insulin sensitization and satiety promotion, GIP-mediated enhancement of insulin secretion and adipose lipid buffering, and glucagon-mediated direct hepatic lipid oxidation and energy expenditure augmentation

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Why GLP-1 Drugs and Heart Protection Are Getting Attention Could a weight loss and diabetes medicine also help protect the heart

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In 2024, he and his colleagues published the first case report on the use of a GLP-1 drug to successfully manage lymphedema in a different breast cancer patient