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Methods Search strategy and selection criteria The systematic review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD420251088025

GGCT channels Gln flux for GSH synthesis and Glc anaplerosis into the TCA cycle ROS act as signaling molecules that regulate mitochondrial function, with mitochondrial morphology intrinsically linked to core processes, including the TCA cycle and oxidative phosphorylation

Prior to the commencement of experiments, these mice underwent an acclimatization period of one week under laboratory conditions

doi:10.1210/jc.2014-3016

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