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Providers evaluate: Body mass index (BMI) Existing medical conditions Current medications Gastrointestinal history Family history of endocrine tumors Pregnancy or breastfeeding status A personalized medical evaluation remains essential before starting any prescription weight-loss medication

The Canadian Patent Database shows the patent, first issued in 2013, is now expired and beyond the period of reversal. Meanwhile, Novo Nordisk retains US patent protection until at least 2032

If these symptoms persist, talk to a healthcare provider

However, many healthcare providers prescribe it off-label for weight loss because semaglutide reduces appetite and food cravings significantly

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Starting with very small meals, avoiding trigger foods, and following the gradual dose escalation schedule significantly reduces nausea severity