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Future studies should validate these targets in preclinical models and explore their translational potential to develop interventions improving the outcomes of patients with SAE

In addition to activating MAPK, H2O2 inhibits phosphatase activities, probably by the direct oxidation of cysteine in the active site of these enzymes

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21st century [edit] Rates of scurvy in the developed world are low due to the greater access to vitamin C-rich foods