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The only benefit may be the possibility of pyruvate decarboxylation by the pyruvate dehydrogenase complex (PDC) [96], which produces the equimolar amount of NADH

doi: 10.21037/jtd-22-475 235 YuL.MengG.HuangB.ZhouX.StavrakisS.WangM.et al

In general, it is considered a multifactorial metabolic disease characterized by several clinical manifestations such as hyperandrogenism, polycystic ovaries aspects on ultrasound and ovulatory dysfunctions which makes it the most common cause of anovulation infertility in women, but also from metabolic problems such as obesity, insulin resistance, hyperinsulinemia and type II diabetes which may enhance cardiovascular complications and other neurological and psychological implication such as anxiety and depression [2, 3]

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A marked sex difference was observed in rats, with a ten-fold greater induction of CYP3A in females than in males and a four-fold greater induction of CYP4A in males than in females

Tofacitinib and newer JAK inhibitors in inflammatory bowel disease-where we are and where we are going