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In type 1 diabetes, the pancreas produces little to no insulin, so patients need external insulin to survive

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Possible complications related to GLP-1 use under anesthesia include: Aspiration due to delayed gastric emptying Hemodynamic instability: pronounced hypotension or bradycardia Altered response to opioids and sedatives, requiring dose changes Perioperative hypoglycemia from additive glucose-lowering effects Nausea and vomiting increasing postoperative airway risk Delayed recovery of bowel function, affecting discharge timing Interference with regional anesthesia sympathetic block assessment Post-Surgery Restart Post-surgery restart of GLP-1 receptor agonists should be done with clear criteria and close coordination to avoid complications and maintain therapeutic goals

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