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In an animal model of diabetes, CoQ10 treatment significantly improved insulin resistance, reduced serum levels of insulin and glucose, and increased levels of the energy-regulating hormone adiponectin six-fold (Amin 2014)

Axonal injury in the CNS might raise the level of NfL in the CSF (Kawarabayashi et al., 2023), hence, from a pathophysiological perspective, the degree of axonal injury or degeneration was positively connected with the amount of NfL in CSF