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Symptoms often include a burning sensation in the chest, commonly referred to as heartburn, which may be accompanied by regurgitation of food or sour liquid

I cover its natural role in plasma and tissues, how levels fall with age, and the surprising breadth of its actionsfrom extracellular matrix remodeling and antioxidant effects to cognitive protection, cardiovascular benefits, and boosted wound healing

T2DM is the main cause of CKD and it has high morbidity in non-diabetic nephropathy

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Unfortunately, they do not reduce the risk of cardiovascular disease or prevent loss of renal function

[DOI] [PubMed] [Google Scholar] Kashima Y, Miki T, Shibasaki T, Ozaki N, Miyazaki M, Yano H, Seino S