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Therefore, considering a broad spectrum of effects that may result from the induction of NO synthesis, a deep analysis of its interaction with potent drugs affecting NO pathways should be performed (e.g., aspirin that has been shown to inhibit eNOS [57])

The moderately strong effect size (Hedges g = 0.67) across multiple randomized controlled trials places oxytocin research on relatively firm ground, though questions about optimal dosing, frequency, and long-term effects remain active areas of investigation

J Biomater Sci Polym Ed 2008;19:969-988