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Classification of AC Separations AC separations are classified into six types (Type I to Type VI) based on the severity of ligament damage and degree of separation: Type I: Minor sprain with no displacement Type II: Partial dislocation with rupture of the AC ligament Type III: Complete dislocation with tearing of both AC and coracoclavicular (CC) ligaments Types IV-VI: Severe dislocations involving displacement of the clavicle in various directions, typically requiring surgery Types I to III are typically managed conservatively, whereas Types IV to VI may require surgical intervention

Toll-like receptor 4 signaling regulates the acute local inflammatory response to injury and the fibrosis/neovascularization of sterile wounds