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Studies show that individuals lacking any endogenous enzyme, termed cross-reactive immunologic material (CRIM) negative, are at high risk of such immune reactions following ERT initiation (139141)
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doi: 10.1186/s12887-022-03275-5 41 IughettiLViviGBalsamoACorriasACrinADelvecchioMet al
10.1111/liv.14990 63 HyndmanD.LiuS.MinerJ
Genome-Wide Screen for Mutants With Reduced Responsiveness to Carnitine Supplementation A genome-wide deletion strain screen for loss of responsiveness to carnitine supplementation during stress conditions was carried out using the haploid BY4741 deletion collection ( ORF ::kanMX4)
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