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Similarly, curcumin modulates lipid metabolism in THP-1-derived macrophages by upregulating lipid transport genes such as CD36/FAT and FABP-4, leading to lipid accumulation and potentially limiting lipid utilization by tumor cells, ultimately inhibiting tumor growth (135, 136)

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Both [30] and [6] created reference datasets for evaluating system performance: [30] curated and manually annotated a Twitter corpus of 57,473 de-duplicated, sampled tweets Footnote 11 , while [6] produced the TwiMed dataset comprising 1,000 annotated tweets and 1,000 PubMed sentences focused on ADEs related to Diclofenac and Lipitor

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